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The Enhanced Recovery After Surgery pathway for posterior cervical surgery: a retrospective propensity-matched cohort study

Ken Porche College of Medicine, University of Florida, Gainesville;
Lillian S. Wells Department of Neurosurgery, University of Florida, Gainesville; and

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Sandra C. Yan College of Medicine, University of Florida, Gainesville;
Lillian S. Wells Department of Neurosurgery, University of Florida, Gainesville; and

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Yusuf Mehkri College of Medicine, University of Florida, Gainesville;

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Sai Sriram College of Medicine, University of Florida, Gainesville;

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Andrew MacNeil College of Medicine, University of Florida, Gainesville;

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Kaitlyn Melnick College of Medicine, University of Florida, Gainesville;
Lillian S. Wells Department of Neurosurgery, University of Florida, Gainesville; and

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Cynthia Garvan Department of Anesthesiology, University of Florida, Gainesville, Florida

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Sasha Vaziri College of Medicine, University of Florida, Gainesville;
Lillian S. Wells Department of Neurosurgery, University of Florida, Gainesville; and

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Christoph Seubert College of Medicine, University of Florida, Gainesville;
Department of Anesthesiology, University of Florida, Gainesville, Florida

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Gregory Murad College of Medicine, University of Florida, Gainesville;
Lillian S. Wells Department of Neurosurgery, University of Florida, Gainesville; and

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Matthew Decker College of Medicine, University of Florida, Gainesville;
Lillian S. Wells Department of Neurosurgery, University of Florida, Gainesville; and

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Adam Polifka College of Medicine, University of Florida, Gainesville;
Lillian S. Wells Department of Neurosurgery, University of Florida, Gainesville; and

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Daniel J. Hoh College of Medicine, University of Florida, Gainesville;
Lillian S. Wells Department of Neurosurgery, University of Florida, Gainesville; and

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Basma Mohamed College of Medicine, University of Florida, Gainesville;
Department of Anesthesiology, University of Florida, Gainesville, Florida

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OBJECTIVE

The Enhanced Recovery After Surgery (ERAS) protocol is a comprehensive, multifaceted approach aimed at improving postoperative outcomes. It incorporates a range of strategies to promote early and more effective recovery, including reducing pain, complications, and length of stay, without increasing readmission rate. To date, ERAS for spine surgery patients has been primarily limited to lumbar surgery and anterior cervical decompression and fusion (ACDF). ERAS has not been previously studied for posterior cervical surgery, which may present a greater opportunity for improvement in patient outcomes with ERAS than ACDF. This single-institution, multi-surgeon study assessed the impact of an ERAS protocol in patients undergoing posterior cervical decompression surgery.

开云体育世界杯赔率

This study included a retrospective consecutive patient cohort with controls that were propensity matched for age, body mass index, sex, home opioid use, surgical levels, Nurick grade, and smoking status. In addition, consecutive patients who underwent posterior cervical decompression surgery for degenerative disease from December 2014 to December 2021 were included. ERAS was implemented in December 2018. Demographic, perioperative, clinical, and radiographic information was gathered. Regression models were created to evaluate length of stay, physiological function, pain levels, and opioid use. The primary focus was length of stay, with secondary outcomes including timing of ambulation, bowel movement, and voiding; daily pain scores; opioid consumption; discharge status; 30-day readmission rates; and reoperation rates.

RESULTS

包括在这项研究中,有366患者of whom were included in multivariate models, and 254 (127 in each cohort) were included on the basis of matching. After propensity matching, patient characteristics, operative procedures, and operative duration were similar between groups. The ERAS cohort had a significantly improved length of stay (3.2 vs 4.7 days, p < 0.0001) and home discharge rate (80% vs 50%, p < 0.001) without an increase in readmission rate. The ERAS cohort had an earlier day of the first ambulation (p = 0.003), bowel movement (p = 0.014), and voiding (p = 0.001). ERAS demonstrated a significantly lower composite complication rate (1.1 vs 1.8, p < 0.0001). ERAS resulted in better maximum pain scores (p = 0.043) and trended toward improved mean pain scores (p = 0.072), although total opioid use was similar.

CONCLUSIONS

Implementing a novel ERAS protocol significantly improved length of stay, return of physiological function, home discharge, complications, and maximum pain score after posterior cervical surgery.

ABBREVIATIONS

ACDF = anterior cervical decompression and fusion ; BIC = Bayesian information criteria ; 中安集团经贸=修正Akaike信息标准 ; CL = cervical laminoplasty ; DVPRS =国防和退伍军人疼痛评定量表 ; ERAS = Enhanced Recovery After Surgery ; IV = intravenous ; LOS = length of stay ; MME = morphine milligram equivalents ; PCA = patient-controlled analgesia ; PCDF = posterior cervical decompression and fusion ; POD = postoperative day .

Supplementary Materials

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Figure from Yu et al. (pp 238–246).
  • 1.

    YangY,WuX,WuW,et al.Enhanced recovery after surgery (ERAS) pathway for microendoscopy-assisted minimally invasive transforaminal lumbar interbody fusion.Clin Neurol Neurosurg.2020;196:106003.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 2.

    KehletH.Multimodal approach to control postoperative pathophysiology and rehabilitation.Br J Anaesth.1997;78(5):606617.

  • 3.

    MendivilAA,BuschJR,RichardsDC,VittoriH,GoldsteinBH.The impact of an enhanced recovery after surgery program on patients treated for gynecologic cancer in the community hospital setting.Int J Gynecol Cancer.2018;28(3):581585.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 4.

    SenturkJC,KristoG,GoldJ,BledayR,WhangE.The development of enhanced recovery after surgery across surgical specialties.J Laparoendosc Adv Surg Tech A.2017;27(9):863870.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 5.

    StowersMDJ,LemanuDP,ColemanB,HillAG,MunroJT.Review article: Perioperative care in enhanced recovery for total hip and knee arthroplasty.J Orthop Surg (Hong Kong).2014;22(3):383392.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 6.

    EpsteinNE.A review article on the benefits of early mobilization following spinal surgery and other medical/surgical procedures.Surg Neurol Int.2014;5(3)(suppl 3):S66S73.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 7.

    MathiesenO,DahlB,ThomsenBA,et al.A comprehensive multimodal pain treatment reduces opioid consumption after multilevel spine surgery.Eur Spine J.2013;22(9):20892096.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 8.

    FleegeC,ArabmotlaghM,AlmajaliA,RauschmannM.Prä- und postoperative Fast-track-Behandlungskonzepte in der Wirbelsäulenchirurgie: Patienteninformation und Patientenkooperation.Orthopade.2014;43(12):1062-1064,1066-1069.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 9.

    LiJ,LiH,XvZK,et al.Enhanced recovery care versus traditional care following laminoplasty: A retrospective case-cohort study.Medicine (Baltimore).2018;97(48):e13195.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 10.

    ChangHK,HuangM,WuJC,HuangWC,WangMY.Less opioid consumption with enhanced recovery after surgery transforaminal lumbar interbody fusion (TLIF): a comparison to standard minimally-invasive TLIF.Neurospine.2020;17(1):228236.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 11.

    AliZS,MaTS,OzturkAK,et al.Pre-optimization of spinal surgery patients: development of a neurosurgical enhanced recovery after surgery (ERAS) protocol.Clin Neurol Neurosurg.2018;164:142153.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 12.

    VenkataHK,van DellenJR.A perspective on the use of an enhanced recovery program in open, non-instrumented day surgery for degenerative lumbar and cervical spinal conditions.J Neurosurg Sci.2018;62(3):245254.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 13.

    GornitzkyAL,FlynnJM,MuhlyWT,SankarWN.A rapid recovery pathway for adolescent idiopathic scoliosis that improves pain control and reduces time to inpatient recovery after posterior spinal fusion.Spine Deform.2016;4(4):288295.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 14.

    AngusM,JacksonK,SmurthwaiteG,et al.The implementation of enhanced recovery after surgery (ERAS) in complex spinal surgery.J Spine Surg.2019;5(1):116123.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 15.

    SoffinEM,WetmoreDS,BarberLA,et al.An enhanced recovery after surgery pathway: association with rapid discharge and minimal complications after anterior cervical spine surgery.Neurosurg Focus.2019;46(4):E9.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 16.

    PorcheK,SamraR,MelnickK,et al.Enhanced recovery after surgery (ERAS) for open transforaminal lumbar interbody fusion: a retrospective propensity-matched cohort study.Spine J.2022;22(3):399410.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 17.

    PorcheK,YanS,MohamedB,et al.Enhanced recovery after surgery (ERAS) improves return of physiological function in frail patients undergoing 1-2 level TLIFs: an observational retrospective cohort study.Spine J.2022;22(9):15131522.

    • Search Google Scholar
    • Export Citation
  • 18.

    CurleyKL,RichardsAE,ZhangN,LyonsMK,NealMT.Enhanced recovery after posterior cervical fusion surgery: a retrospective case series.Interdiscip Neurosurg.2021;25:101143.

    • Search Google Scholar
    • Export Citation
  • 19.

    WadhwaH,SharmaJ,VarshneyaK,et al.Anterior cervical discectomy and fusion versus laminoplasty for multilevel cervical spondylotic myelopathy: a national administrative database analysis.World Neurosurg.2021;152:e738e744.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 20.

    ShamjiMF,CookC,PietrobonR,TackettS,BrownC,IsaacsRE.Impact of surgical approach on complications and resource utilization of cervical spine fusion: a nationwide perspective to the surgical treatment of diffuse cervical spondylosis.Spine J.2009;9(1):3138.

    • Search Google Scholar
    • Export Citation
  • 21.

    JiangYQ,LiXL,ZhouXG,et al.A prospective randomized trial comparing anterior cervical discectomy and fusion versus plate-only open-door laminoplasty for the treatment of spinal stenosis in degenerative diseases.Eur Spine J.2017;26(4):11621172.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 22.

    ColeT,VeeravaguA,ZhangM,AzadTD,DesaiA,RatliffJK.前部和后部相乘的方法ilevel degenerative cervical disease: a retrospective propensity score-matched study of the MarketScan database.Spine (Phila Pa 1976).2015;40(13):10331038.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 23.

    NurickS.The pathogenesis of the spinal cord disorder associated with cervical spondylosis.Brain.1972;95(1):87100.

  • 24.

    Roy-CamilleR,SaillantG,LavilleC,BenazetJP.Treatment of lower cervical spinal injuries—C3 to C7.Spine (Phila Pa 1976).1992;17(10)(suppl):S442S446.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 25

    HirabayashiK,WatanabeK,WakanoK,SuzukiN,SatomiK,IshiiY.Expansive open-door laminoplasty for cervical spinal stenotic myelopathy.Spine (Phila Pa 1976).1983;8(7):693699.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 26.

    HoD,ImaiK,KingG,StuartEA.MatchIt: nonparametric preprocessing for parametric causal inference.J Stat Softw.2011;42(8):128.

    • Search Google Scholar
    • Export Citation
  • 27.

    HarrellFEJr.Regression Modeling Strategies: With Applications to Linear Models, Logistic and Ordinal Regression, and Survival Analysis.2nd ed.Springer;2015.

    • Search Google Scholar
    • Export Citation
  • 28.

    HurvichCM,TsaiCL.Bias of the corrected AIC criterion for underfitted regression and time series models.Biometrika.1991;78(3):499509.

    • Search Google Scholar
    • Export Citation
  • 29

    SchwarzG.Estimating the dimension of a model.Ann Stat.1978;6(2):461464.

  • 30

    WangMY,ChangHK,GrossmanJ.Reduced acute care costs with the ERAS® minimally invasive transforaminal lumbar interbody fusion compared with conventional minimally invasive transforaminal lumbar interbody fusion.开云体育app官方网站下载入口.2018;83(4):827834.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 31.

    BohlDD,LouiePK,ShahN,et al.Multimodal versus patient-controlled analgesia after an anterior cervical decompression and fusion.Spine (Phila Pa 1976).2016;41(12):994998.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 32.

    ElderJB,HohDJ,LiuCY,WangMY.Postoperative continuous paravertebral anesthetic infusion for pain control in posterior cervical spine surgery: a case-control study.开云体育app官方网站下载入口.2010;66(3)(Suppl Operative):99107.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 33.

    SanfordZ,BrodaA,TaylorH,TurcotteJ,PattonCM.Predictive risk factors associated with increased opioid use among patients undergoing elective spine surgery.Int J Spine Surg.2020;14(2):189194.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 34.

    NygrenJ,ThackerJ,CarliF,et al.Guidelines for perioperative care in elective rectal/pelvic surgery: Enhanced Recovery After Surgery (ERAS®) Society recommendations.World J Surg.2013;37(2):285305.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 35.

    SoffinEM,BeckmanJD,TsengA,et al.Enhanced recovery after lumbar spine fusion: a randomized controlled trial to assess the quality of patient recovery.Anesthesiology.2020;133(2):350363.

    • PubMed
    • Search Google Scholar
    • Export Citation

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