Spinopelvic sagittal alignment and compensation in adult cervical kyphotic deformity has not been thoroughly evaluated. This study found that adult cervical deformity is associated with upper cervical hyperlordosis and thoracic hypokyphosis. In severe kyphotic deformity and sagittal malalignment, thoracolumbar junction kyphosis and lumbar hyperlordosis also develop. There is significant correction of these compensatory mechanisms following cervical reconstruction. A better understanding of spinopelvic sagittal compensation will help guide surgical indications and parameters for cervical reconstruction.
Depression and anxiety have been linked to inferior surgical outcomes for spine disorders; however, it remains unclear if patients with comorbid depression and anxiety have even worse outcomes. In a bispective analysis of 1141 patients who underwent surgery for cervical spondylotic myelopathy (CSM), comparison of patients who self-reported both depression and anxiety with patients reporting either symptom alone was not associated with worse 24-month outcomes. These findings fail to support an additive impact of both self-reported psychological symptoms on postoperative outcomes and quality of life.
The objective of this study was to use a patient-specific finite element model to compare changes in spinal cord biomechanics after laminectomy with fusion, laminectomy, and laminoplasty. Spinal cord stress and strain were lowest after laminectomy with fusion compared with motion-preserving approaches such as laminoplasty and laminectomy. This study highlights the potential utility of patient-specific finite element modeling of the spinal cord to predict postsurgical spinal cord stress/strain using simulated surgical interventions.
Researchers evaluated the comprehensive outcomes of lumbar fusion in elderly patients older than 85 years with mid-term follow-up. Lumbar fusion in patients older than 85 years was performed with satisfactory postoperative outcomes despite the greater incidence of lumbar vertebral fractures and postoperative delirium. This study provides important information for clinicians performing lumbar fusion.
The authors conducted a study to compare clinical and patient-reported outcomes between patients who underwent lumbar spine surgery with and without workers' compensation (WC) status. The results showed significantly worse postoperative pain, disability, and quality of life, as well as delayed return to work, in patients receiving WC. The study adds value by generating discussion among peers to analyze reasons for the increased correlation between adverse outcomes and compensation status, as well as generating ideas to equalize outcomes between both groups.
Researchers investigated the influence of correction surgery on pulmonary function in patients with thoracic spinal posttubercular kyphosis. Patients' pulmonary function significantly improved after surgery, and local kyphosis correction showed a significant positive correlation with improvement in pulmonary function and lung volume. The clinical efficacy of posterior vertebral column resection on spinal posttubercular kyphosis was further evaluated, which provides more guidance on treating thoracic spinal kyphotic deformity.
This study investigated the effects of autoimmune diseases on postoperative medical complications after adult spinal deformity (ASD) correction. Patients with autoimmune disease had higher complication rates and worse patient-reported outcome measures compared with controls. Multidisciplinary planning and full disclosure of possible adverse effects should be conducted prior to ASD surgery in patients with autoimmune disease.
The purpose of this study was to determine the poor prognostic factors of balloon kyphoplasty in the treatment of fractures of the most distal or distal-adjacent vertebrae of ankylosing spines with diffuse idiopathic skeletal hyperplasia. Bone healing was more likely to be delayed in patients with wedge angle changes ≥ 10°. This study demonstrates the indication for balloon kyphoplasty in osteoporotic vertebral fractures in patients with diffuse idiopathic skeletal hyperplasia.
By comparing the natural history progression of adult spinal deformity with the progression of patients with suboptimal outcomes after surgical correction, this study found that those who had suboptimal outcomes after surgical correction were more likely to achieve favorable minimal clinically important difference in health-related quality of life measures compared with those who did not undergo surgical correction.
Researchers investigated the role of dorsal root entry zone lesioning in managing the continuous and paroxysmal components of chronic medically refractory pain following brachial plexus avulsion. Dorsal root entry zone lesioning is effective and safe in relieving both pain components without major complications—with more robustness for paroxysmal attacks. Whereas patients showed excellent pain relief over short-term follow-up, it dropped but was still robust by the 3-year follow-up. This study better clarifies the patient subgroups who received the most benefit.
The authors created a novel bone graft substitute material and used a rat model of spinal fusion to compare the efficacy of this new material against that of the widely used Infuse bone graft product in the setting of different concentrations of recombinant human bone morphogenetic protein-2 (rhBMP-2). The new material resulted in complete fusions with bone volume and quality superior to that seen with the use of Infuse collagen sponges with a 10-fold higher concentration of rhBMP-2. Additional work is needed to evaluate this new material more fully as a bone graft substitute.
小说脊柱内窥镜手术是藐视的需要for traditional in-person postoperative care, counseling, and follow-up. In this study, the authors demonstrate the safety and feasibility of virtual postoperative care and outcome collection in this patient population using a novel smartphone app. The patients expressed a high rate of satisfaction with app-based virtual postoperative care, and more than 75% of patients provided postoperative patient-reported outcomes at 3 months after surgery. App-based patient follow-up provides a highly flexible platform to power multicenter research endeavors. Importantly, implementation eases the burden of postoperative care and elevates the patient's postoperative experience.
Strategies such as collecting patient-reported outcome measures, leveraging immersive technology, and utilizing patient review systems can enhance a clinical practice and build a research program. Such activities need the presence of a team to mechanize research output and maximize productivity.
This large study of nearly 300,000 spine surgery patients in the American College of Surgeons National Surgical Quality Improvement Program database (2015-2019) compares the discriminative threshold of the retrospective Risk Analysis Index (RAI) with the 5-factor modified frailty index (mFI-5) for predicting postoperative mortality. The RAI demonstrated superior discrimination compared with the mFI-5 in predicting postoperative mortality (C-statistic 0.80) in the overall cohort and in the trauma and infection cohorts. The RAI is preferred to the mFI-5 for frailty screening in spine surgery patients.