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Localization of stimulating electrodes in patients with Parkinson disease by using a three-dimensional atlas—magnetic resonance imaging coregistration method

Jérôme Yelnik Institut National de la Santé et de la Recherche Médicale U289, Centre d'Investigation Clinique, Fédération de Neurologie, Services de Neuroradiologie, Neurochirurgie, et Neurophysiologie, Centre National de la Recherche Scientifique UPR640, Hôpital de la Salpêtrière, Paris; and Institut National de la Recherche en Informatique et en Automatique, Epidaure Project, Sophia Antipolis, France

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Philippe Damier Institut National de la Santé et de la Recherche Médicale U289, Centre d'Investigation Clinique, Fédération de Neurologie, Services de Neuroradiologie, Neurochirurgie, et Neurophysiologie, Centre National de la Recherche Scientifique UPR640, Hôpital de la Salpêtrière, Paris; and Institut National de la Recherche en Informatique et en Automatique, Epidaure Project, Sophia Antipolis, France

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Sophie Demeret Institut National de la Santé et de la Recherche Médicale U289, Centre d'Investigation Clinique, Fédération de Neurologie, Services de Neuroradiologie, Neurochirurgie, et Neurophysiologie, Centre National de la Recherche Scientifique UPR640, Hôpital de la Salpêtrière, Paris; and Institut National de la Recherche en Informatique et en Automatique, Epidaure Project, Sophia Antipolis, France

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David Gervais Institut National de la Santé et de la Recherche Médicale U289, Centre d'Investigation Clinique, Fédération de Neurologie, Services de Neuroradiologie, Neurochirurgie, et Neurophysiologie, Centre National de la Recherche Scientifique UPR640, Hôpital de la Salpêtrière, Paris; and Institut National de la Recherche en Informatique et en Automatique, Epidaure Project, Sophia Antipolis, France

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Eric Bardinet Institut National de la Santé et de la Recherche Médicale U289, Centre d'Investigation Clinique, Fédération de Neurologie, Services de Neuroradiologie, Neurochirurgie, et Neurophysiologie, Centre National de la Recherche Scientifique UPR640, Hôpital de la Salpêtrière, Paris; and Institut National de la Recherche en Informatique et en Automatique, Epidaure Project, Sophia Antipolis, France

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Boulos-Paul Bejjani Institut National de la Santé et de la Recherche Médicale U289, Centre d'Investigation Clinique, Fédération de Neurologie, Services de Neuroradiologie, Neurochirurgie, et Neurophysiologie, Centre National de la Recherche Scientifique UPR640, Hôpital de la Salpêtrière, Paris; and Institut National de la Recherche en Informatique et en Automatique, Epidaure Project, Sophia Antipolis, France

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Chantal François Institut National de la Santé et de la Recherche Médicale U289, Centre d'Investigation Clinique, Fédération de Neurologie, Services de Neuroradiologie, Neurochirurgie, et Neurophysiologie, Centre National de la Recherche Scientifique UPR640, Hôpital de la Salpêtrière, Paris; and Institut National de la Recherche en Informatique et en Automatique, Epidaure Project, Sophia Antipolis, France

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Jean-Luc Houeto Institut National de la Santé et de la Recherche Médicale U289, Centre d'Investigation Clinique, Fédération de Neurologie, Services de Neuroradiologie, Neurochirurgie, et Neurophysiologie, Centre National de la Recherche Scientifique UPR640, Hôpital de la Salpêtrière, Paris; and Institut National de la Recherche en Informatique et en Automatique, Epidaure Project, Sophia Antipolis, France

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Isabelle Arnulf Institut National de la Santé et de la Recherche Médicale U289, Centre d'Investigation Clinique, Fédération de Neurologie, Services de Neuroradiologie, Neurochirurgie, et Neurophysiologie, Centre National de la Recherche Scientifique UPR640, Hôpital de la Salpêtrière, Paris; and Institut National de la Recherche en Informatique et en Automatique, Epidaure Project, Sophia Antipolis, France

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Didier Dormont Institut National de la Santé et de la Recherche Médicale U289, Centre d'Investigation Clinique, Fédération de Neurologie, Services de Neuroradiologie, Neurochirurgie, et Neurophysiologie, Centre National de la Recherche Scientifique UPR640, Hôpital de la Salpêtrière, Paris; and Institut National de la Recherche en Informatique et en Automatique, Epidaure Project, Sophia Antipolis, France

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Damien Galanaud Institut National de la Santé et de la Recherche Médicale U289, Centre d'Investigation Clinique, Fédération de Neurologie, Services de Neuroradiologie, Neurochirurgie, et Neurophysiologie, Centre National de la Recherche Scientifique UPR640, Hôpital de la Salpêtrière, Paris; and Institut National de la Recherche en Informatique et en Automatique, Epidaure Project, Sophia Antipolis, France

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Bernard Pidoux Institut National de la Santé et de la Recherche Médicale U289, Centre d'Investigation Clinique, Fédération de Neurologie, Services de Neuroradiologie, Neurochirurgie, et Neurophysiologie, Centre National de la Recherche Scientifique UPR640, Hôpital de la Salpêtrière, Paris; and Institut National de la Recherche en Informatique et en Automatique, Epidaure Project, Sophia Antipolis, France

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Philippe Cornu Institut National de la Santé et de la Recherche Médicale U289, Centre d'Investigation Clinique, Fédération de Neurologie, Services de Neuroradiologie, Neurochirurgie, et Neurophysiologie, Centre National de la Recherche Scientifique UPR640, Hôpital de la Salpêtrière, Paris; and Institut National de la Recherche en Informatique et en Automatique, Epidaure Project, Sophia Antipolis, France

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Yves Agid Institut National de la Santé et de la Recherche Médicale U289, Centre d'Investigation Clinique, Fédération de Neurologie, Services de Neuroradiologie, Neurochirurgie, et Neurophysiologie, Centre National de la Recherche Scientifique UPR640, Hôpital de la Salpêtrière, Paris; and Institut National de la Recherche en Informatique et en Automatique, Epidaure Project, Sophia Antipolis, France

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Object.The aim of this study was to correlate the clinical improvement in patients with Parkinson disease (PD) treated using deep brain stimulation (DBS) of the subthalamic nucleus (STN) with the precise anatomical localization of stimulating electrodes.

Methods.Localization was determined by superimposing figures from an anatomical atlas with postoperative magnetic resonance (MR) images obtained in each patient. This approach was validated by an analysis of experimental and clinical MR images of the electrode, and the development of a three-dimensional (3D) atlas—MR imaging coregistration method. The PD motor score was assessed through two contacts for each of two electrodes implanted in 10 patients: the “therapeutic contact” and the “distant contact” (that is, the next but one to the therapeutic contact). Seventeen therapeutic contacts were located within or on the border of the STN, most of which were associated with significant improvement of the four PD symptoms tested. Therapeutic contacts located in other structures (zona incerta, lenticular fasciculus, or midbrain reticular formation) were also linked to a significant positive effect. Stimulation applied through distant contacts located in the STN improved symptoms of PD, whereas that delivered through distant contacts in the remaining structures had variable effects ranging from worsening of symptoms to their improvement.

Conclusions.The authors have demonstrated that 3D atlas—MR imaging coregistration is a reliable method for the precise localization of DBS electrodes on postoperative MR images. In addition, they have confirmed that although the STN is the main target during DBS treatment for PD, stimulation of surrounding regions, particularly the zona incerta or the lenticular fasciculus, can also improve symptoms of PD.

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  • 1.

    AlexanderGE,&CrutcherMD:Functional architecture of basal ganglia circuits: neural substrates of parallel processing.Trends Neurosci13:266271,1990Alexander GE, Crutcher MD: Functional architecture of basal ganglia circuits: neural substrates of parallel processing.Trends Neurosci 13:266–271, 1990

    • Search Google Scholar
    • Export Citation
  • 2.

    AzizTZ,,PeggsD,&SambrookMA,et al:Lesion of the subthalamic nucleus for the alleviation of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced parkinsonism in the primate.Mov Disord6:288292,1991Aziz TZ, Peggs D, Sambrook MA, et al: Lesion of the subthalamic nucleus for the alleviation of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced parkinsonism in the primate.Mov Disord 6:288–292, 1991

    • Search Google Scholar
    • Export Citation
  • 3.

    BejjaniBP,,DormontD,&PidouxB,et al:Bilateral subthalamic stimulation for Parkinson's disease by using three-dimensional stereotactic magnetic resonance imaging and electrophysiological guidance.J Neurosurg92:615625,2000Bejjani BP, Dormont D, Pidoux B, et al: Bilateral subthalamic stimulation for Parkinson's disease by using three-dimensional stereotactic magnetic resonance imaging and electrophysiological guidance.J Neurosurg 92:615–625, 2000

    • Search Google Scholar
    • Export Citation
  • 4.

    BenabidAL,,KrackPP,&BenazzouzA,et al:Deep brain stimulation of the subthalamic nucleus for Parkinson's disease: methodologic aspects and clinical criteria.Neurology55(Suppl 6):S40S44,2000Benabid AL, Krack PP, Benazzouz A, et al: Deep brain stimulation of the subthalamic nucleus for Parkinson's disease: methodologic aspects and clinical criteria.Neurology 55 (Suppl 6):S40–S44, 2000

    • Search Google Scholar
    • Export Citation
  • 5.

    BenazzouzA,,GrossC,&FégerJ,et al:Reversal of rigidity and improvement of motor performance by subthalamic high-frequency stimulation in MPTP-treated monkeys.Eur J Neurosci5:382389,1993Benazzouz A, Gross C, Féger J, et al: Reversal of rigidity and improvement of motor performance by subthalamic high-frequency stimulation in MPTP-treated monkeys.Eur J Neurosci 5:382–389, 1993

    • Search Google Scholar
    • Export Citation
  • 6.

    BergmanH,,WichmannT,&DeLongMR:Reversal of experimental parkinsonism by lesions of the subthalamic nucleus.Science249:14361438,1990Bergman H, Wichmann T, DeLong MR: Reversal of experimental parkinsonism by lesions of the subthalamic nucleus.Science 249:1436–1438, 1990

    • Search Google Scholar
    • Export Citation
  • 7.

    BourgeoisG,,MagninM,&MorelA,et al:Accuracy of MRI-guided stereotactic thalamic functional neurosurgery.Neuroradiology41:636645,1999Bourgeois G, Magnin M, Morel A, et al: Accuracy of MRI-guided stereotactic thalamic functional neurosurgery.神经放射学41:636–645, 1999

    • Search Google Scholar
    • Export Citation
  • 8.

    The Deep-Brain Stimulation for Parkinson's Disease Study Group:Deep-brain stimulation of the subthalamic nucleus or the pars interna of the globus pallidus in Parkinson's disease.N Engl J Med345:956963,2001The Deep-Brain Stimulation for Parkinson's Disease Study Group: Deep-brain stimulation of the subthalamic nucleus or the pars interna of the globus pallidus in Parkinson's disease.N Engl J Med 345:956–963, 2001

    • Search Google Scholar
    • Export Citation
  • 9.

    DeLongMR:Primate models of movement disorders of basal ganglia origin.Trends Neurosci13:281285,1990DeLong MR: Primate models of movement disorders of basal ganglia origin.Trends Neurosci 13:281–285, 1990

    • Search Google Scholar
    • Export Citation
  • 10.

    DormontD,,CornuP,&PidouxB,et al:Chronic thalamic stimulation with three-dimensional MR stereotactic guidance.AJNR18:10931107,1997Dormont D, Cornu P, Pidoux B, et al: Chronic thalamic stimulation with three-dimensional MR stereotactic guidance.AJNR 18:1093–1107, 1997

    • Search Google Scholar
    • Export Citation
  • 11.

    DormontD,,ZerahM,&CornuP,et al:A technique of measuring the precision of an MR-guided stereotaxic installation using anatomic specimens.AJNR15:365371,1994Dormont D, Zerah M, Cornu P, et al: A technique of measuring the precision of an MR-guided stereotaxic installation using anatomic specimens.AJNR 15:365–371, 1994

    • Search Google Scholar
    • Export Citation
  • 12.

    FahnS,&EltonRL,Members of the UPDRS Development Committee:Unified Parkinson's Disease Rating Scale, inFahnS,,MarsdenCD,&GoldsteinM,et al(eds):Recent Developments in Parkinson's Disease.Florham Park, NJ:Macmillan Healthcare Information,1987, Vol2, pp153163Fahn S, Elton RL, Members of the UPDRS Development Committee: Unified Parkinson's Disease Rating Scale, in Fahn S, Marsden CD, Goldstein M, et al (eds):Recent Developments in Parkinson's Disease.Florham Park, NJ: Macmillan Healthcare Information, 1987, Vol 2, pp 153–163

    • Search Google Scholar
    • Export Citation
  • 13.

    弗朗哥isC,,YelnikJ,&PercheronG:A stereotaxic atlas of the basal ganglia in macaques.Brain Res Bull41:151158,1996弗朗哥is C, Yelnik J, Percheron G: A stereotaxic atlas of the basal ganglia in macaques.Brain Res Bull 41:151–158, 1996

    • Search Google Scholar
    • Export Citation
  • 14.

    GaoDM,,BenazzouzA,&PiallatB,et al:High-frequency stimulation of the subthalamic nucleus suppresses experimental resting tremor in the monkey.Neuroscience88:201212,1999Gao DM, Benazzouz A, Piallat B, et al: High-frequency stimulation of the subthalamic nucleus suppresses experimental resting tremor in the monkey.Neuroscience 88:201–212, 1999

    • Search Google Scholar
    • Export Citation
  • 15.

    GrossRE,,LombardiWJ,&HutchisonWD,et al:Variability in lesion location after microelectrode-guided pallidotomy for Parkinson's disease: anatomical, physiological, and technical factors that determine lesion distribution.J Neurosurg90:468477,1999Gross RE, Lombardi WJ, Hutchison WD, et al: Variability in lesion location after microelectrode-guided pallidotomy for Parkinson's disease: anatomical, physiological, and technical factors that determine lesion distribution.J Neurosurg 90:468–477, 1999

    • Search Google Scholar
    • Export Citation
  • 16.

    GuridiJ,,Rodriguez-OrozMC,&LozanoAM,et al:Targeting the basal ganglia for deep brain stimulation in Parkinson's disease.Neurology55(Suppl 6):S21S28,2000Guridi J, Rodriguez-Oroz MC, Lozano AM, et al: Targeting the basal ganglia for deep brain stimulation in Parkinson's disease.Neurology 55 (Suppl 6):S21–S28, 2000

    • Search Google Scholar
    • Export Citation
  • 17.

    HarizMI,&BergenheimAT:A comparative study on ventriculographic and computerized tomography-guided determinations of brain targets in functional stereotaxis.J Neurosurg73:565571,1990Hariz MI, Bergenheim AT: A comparative study on ventriculographic and computerized tomography-guided determinations of brain targets in functional stereotaxis.J Neurosurg 73:565–571, 1990

    • Search Google Scholar
    • Export Citation
  • 18.

    HirschEC,,PerierC,&OrieuxG,et al:Metabolic effects of nigrostriatal denervation in basal ganglia.Trends Neurosci23:S78S85,2000Hirsch EC, Perier C, Orieux G, et al: Metabolic effects of nigrostriatal denervation in basal ganglia.Trends Neurosci 23:S78–S85, 2000

    • Search Google Scholar
    • Export Citation
  • 19.

    HoehnMM,&YahrMD:Parkinsonism: onset, progression and mortality.Neurology17:427442,1967Hoehn MM, Yahr MD: Parkinsonism: onset, progression and mortality.Neurology 17:427–442, 1967

    • Search Google Scholar
    • Export Citation
  • 20.

    HouetoJL,,DamierP,&BejjaniPB,et al:Subthalamic stimulation in Parkinson disease: a multidisciplinary approach.Arch Neurol57:461465,2000Houeto JL, Damier P, Bejjani PB, et al: Subthalamic stimulation in Parkinson disease: a multidisciplinary approach.Arch Neurol 57:461–465, 2000

    • Search Google Scholar
    • Export Citation
  • 21.

    HutchisonWD,,AllanRJ,&OpitzH,et al:Neurophysiological identification of the subthalamic nucleus in surgery for Parkinson's disease.Ann Neurol44:622628,1998Hutchison WD, Allan RJ, Opitz H, et al: Neurophysiological identification of the subthalamic nucleus in surgery for Parkinson's disease.Ann Neurol 44:622–628, 1998

    • Search Google Scholar
    • Export Citation
  • 22.

    KrackP,,PollakP,&LimousinP,et al:Subthalamic nucleus or internal pallidal stimulation in young onset Parkinson's disease.Brain121:451457,1998Krack P, Pollak P, Limousin P, et al: Subthalamic nucleus or internal pallidal stimulation in young onset Parkinson's disease.Brain 121:451–457, 1998

    • Search Google Scholar
    • Export Citation
  • 23.

    KumarR,,LangAE,&Rodriguez-OrozMC,et al:Deep brain stimulation of the globus pallidus pars interna in advanced Parkinson's disease.Neurology55(Suppl 6):S34S39,2000Kumar R, Lang AE, Rodriguez-Oroz MC, et al: Deep brain stimulation of the globus pallidus pars interna in advanced Parkinson's disease.Neurology 55 (Suppl 6):S34–S39, 2000

    • Search Google Scholar
    • Export Citation
  • 24.

    KumarR,,LozanoAM,&SimeE,et al:Comparative effects of unilateral and bilateral subthalamic nucleus deep brain stimulation.Neurology53:561566,1999Kumar R, Lozano AM, Sime E, et al: Comparative effects of unilateral and bilateral subthalamic nucleus deep brain stimulation.Neurology 53:561–566, 1999

    • Search Google Scholar
    • Export Citation
  • 25.

    LimousinP,,KrackP,&PollakP,et al:Electrical stimulation of the subthalamic nucleus in advanced Parkinson's disease.N Engl J Med339:11051111,1998利穆赞P,布莱恩的P, Pollak P, et al:电timulation of the subthalamic nucleus in advanced Parkinson's disease.N Engl J Med 339:1105–1111, 1998

    • Search Google Scholar
    • Export Citation
  • 26.

    LimousinP,,PollakP,&BenazzouzA,et al:Bilateral subthalamic nucleus stimulation for severe Parkinson's disease.Mov Disord10:672674,1995Limousin P, Pollak P, Benazzouz A, et al: Bilateral subthalamic nucleus stimulation for severe Parkinson's disease.Mov Disord 10:672–674, 1995

    • Search Google Scholar
    • Export Citation
  • 27.

    LorensonWE,&ClineHE:Marching cubes: a high resolution 3D surface construction algorithm.Comput Graph21:163169,1987Lorenson WE, Cline HE: Marching cubes: a high resolution 3D surface construction algorithm.Comput Graph 21:163–169, 1987

    • Search Google Scholar
    • Export Citation
  • 28.

    OlanowCW,,BrinMF,&ObesoJA:The role of deep brain stimulation as a surgical treatment for Parkinson's disease.Neurology55(Suppl 6):S60S66,2000Olanow CW, Brin MF, Obeso JA: The role of deep brain stimulation as a surgical treatment for Parkinson's disease.Neurology 55 (Suppl 6):S60–S66, 2000

    • Search Google Scholar
    • Export Citation
  • 29.

    ParentA:Carpenter's Human Neuroanatomy,ed 9.Baltimore:Williams & Wilkins,1996Parent A:Carpenter's Human Neuroanatomy, ed 9.Baltimore: Williams & Wilkins, 1996

    • Search Google Scholar
    • Export Citation
  • 30.

    PercheronG:Ventricular landmarks for thalamic stereotaxy in Macaca.J Med Primatol4:217244,1975Percheron G: Ventricular landmarks for thalamic stereotaxy in Macaca.J Med Primatol 4:217–244, 1975

    • Search Google Scholar
    • Export Citation
  • 31.

    PerierC,,VilaM,&FégerJ,et al:Functional activity of zona incerta neurons is altered after nigrostriatal denervation in hemiparkinsonian rats.Exp Neurol162:215224,2000Perier C, Vila M, Féger J, et al: Functional activity of zona incerta neurons is altered after nigrostriatal denervation in hemiparkinsonian rats.Exp Neurol 162:215–224, 2000

    • Search Google Scholar
    • Export Citation
  • 32.

    RocheA,,MalandainG,&PennecX,et al:The correlation ratio as a new similarity measure for multimodal image registration.Lect Notes Comput Sci1496:11151124,1998Roche A, Malandain G, Pennec X, et al: The correlation ratio as a new similarity measure for multimodal image registration.Lect Notes Comput Sci 1496:1115–1124, 1998

    • Search Google Scholar
    • Export Citation
  • 33.

    SchaltenbrandG,&WahrenW:Atlas for Stereotaxy of the Human Brain,ed 2.Stuttgart:Thieme,1977Schaltenbrand G, Wahren W:Atlas for Stereotaxy of the Human Brain, ed 2.Stuttgart: Thieme, 1977

    • Search Google Scholar
    • Export Citation
  • 34.

    SchuurmanPR,,de BieRM,&MajoieCB,et al:A prospective comparison between three-dimensional magnetic resonance imaging and ventriculography for target-coordinate determination in frame-based functional stereotactic neurosurgery.J Neurosurg91:911914,1999Schuurman PR, de Bie RM, Majoie CB, et al: A prospective comparison between three-dimensional magnetic resonance imaging and ventriculography for target-coordinate determination in frame-based functional stereotactic neurosurgery.J Neurosurg 91:911–914, 1999

    • Search Google Scholar
    • Export Citation
  • 35.

    StarrPA,,VitekJL,&BakayRAE:Ablative surgery and deep brain stimulation for Parkinson's disease.开云体育app官方网站下载入口43:9891015,1998Starr PA, Vitek JL, Bakay RAE: Ablative surgery and deep brain stimulation for Parkinson's disease.Neurosurgery 43:989–1015, 1998

    • Search Google Scholar
    • Export Citation
  • 36.

    StarrPA,,VitekJL,&DeLongM,et al:Magnetic resonance imaging-based stereotactic localization of the globus pallidus and subthalamic nucleus.开云体育app官方网站下载入口44:303314,1999Starr PA, Vitek JL, DeLong M, et al: Magnetic resonance imaging-based stereotactic localization of the globus pallidus and subthalamic nucleus.Neurosurgery 44:303–314, 1999

    • Search Google Scholar
    • Export Citation
  • 37.

    TalairachJ,,DavidM,&TournouxP,et al:Atlas d'Anatomie Stéréotaxique: Repérage Radiologique Indirect des Noyaux Gris Centraux des Régions Mésencéphalo-Sous-Optique et Hypothalamique de L'homme.Paris:Masson,1957Talairach J, David M, Tournoux P, et al:Atlas d'Anatomie Stéréotaxique: Repérage Radiologique Indirect des Noyaux Gris Centraux des Régions Mésencéphalo-Sous-Optique et Hypothalamique de L'homme.Paris: Masson, 1957

    • Search Google Scholar
    • Export Citation
  • 38.

    TalairachJ,&TournouxP:Co-Planar Stereotaxic Atlas of the Human Brain: 3-Dimensional Proportional System: An Approach to Cerebral Imaging.New York:Thieme Medical Publishers,1988Talairach J, Tournoux P:Co-Planar Stereotaxic Atlas of the Human Brain: 3-Dimensional Proportional System: An Approach to Cerebral Imaging.New York: Thieme Medical Publishers, 1988

    • Search Google Scholar
    • Export Citation
  • 39.

    TaskerRR,,DostrovskyJO,&DolanEJ:Computerized tomography (CT) is just as accurate as ventriculography for functional stereotactic thalamotomy.Stereotact Funct Neurosurg57:157166,1991Tasker RR, Dostrovsky JO, Dolan EJ: Computerized tomography (CT) is just as accurate as ventriculography for functional stereotactic thalamotomy.Stereotact Funct Neurosurg 57:157–166, 1991

    • Search Google Scholar
    • Export Citation
  • 40.

    ValldeoriolaF,,PilleriM,&TolosaE,et al:Bilateral subthalamic stimulation monotherapy in advanced Parkinson's disease: longterm follow-up of patients.Mov Disord17:125132,2002Valldeoriola F, Pilleri M, Tolosa E, et al: Bilateral subthalamic stimulation monotherapy in advanced Parkinson's disease: longterm follow-up of patients.Mov Disord 17:125–132, 2002

    • Search Google Scholar
    • Export Citation
  • 41.

    VilaM,,LevyR,&HerreroMT,et al:Consequences of nigrostriatal denervation on the functioning of the basal ganglia in human and nonhuman primates: an in situ hybridization study of cytochrome oxidase subunit I mRNA.J Neurosci17:765773,1997Vila M, Levy R, Herrero MT, et al: Consequences of nigrostriatal denervation on the functioning of the basal ganglia in human and nonhuman primates: an in situ hybridization study of cytochrome oxidase subunit I mRNA.J Neurosci 17:765–773, 1997

    • Search Google Scholar
    • Export Citation
  • 42.

    VilaM,,PerierC,&FégerJ,et al:Evolution of changes in neuronal activity in the subthalamic nucleus of rats with unilateral lesion of the substantia nigra assessed by metabolic and electrophysiological measurements.Eur J Neurosci12:337344,2000Vila M, Perier C, Féger J, et al: Evolution of changes in neuronal activity in the subthalamic nucleus of rats with unilateral lesion of the substantia nigra assessed by metabolic and electrophysiological measurements.Eur J Neurosci 12:337–344, 2000

    • Search Google Scholar
    • Export Citation
  • 43.

    VogesJ,,VolkmannJ,&AllertN,et al:Bilateral high-frequency stimulation in the subthalamic nucleus for the treatment of Parkinson disease: correlation of therapeutic effect with anatomical electrode position.J Neurosurg96:269279,2002Voges J, Volkmann J, Allert N, et al: Bilateral high-frequency stimulation in the subthalamic nucleus for the treatment of Parkinson disease: correlation of therapeutic effect with anatomical electrode position.J Neurosurg 96:269–279, 2002

    • Search Google Scholar
    • Export Citation
  • 44.

    WelterML,,HouetoJL,&Tezenas du MontcelS,et al:Clinical predictive factors of subthalamic stimulation in Parkinson's disease.Brain125:575583,2002Welter ML, Houeto JL, Tezenas du Montcel S, et al: Clinical predictive factors of subthalamic stimulation in Parkinson's disease.Brain 125:575–583, 2002

    • Search Google Scholar
    • Export Citation
  • 45.

    YelnikJ,,DamierP,&BejjaniBP,et al:Functional mapping of the human globus pallidus: contrasting effect of stimulation in the internal and external pallidum in Parkinson's disease.Neuroscience101:7787,2000Yelnik J, Damier P, Bejjani BP, et al: Functional mapping of the human globus pallidus: contrasting effect of stimulation in the internal and external pallidum in Parkinson's disease.Neuroscience 101:77–87, 2000

    • Search Google Scholar
    • Export Citation
  • 46.

    ZonenshaynM,,RezaiAR,&MogilnerAY,et al:Comparison of anatomic and neurophysiological methods for subthalamic nucleus targeting.开云体育app官方网站下载入口47:282294,2000Zonenshayn M, Rezai AR, Mogilner AY, et al: Comparison of anatomic and neurophysiological methods for subthalamic nucleus targeting.Neurosurgery 47:282–294, 2000

    • Search Google Scholar
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