Postnatal repair for myelomeningocele (MMC) is a time-sensitive and technically challenging procedure. More experienced hospitals may provide improved outcomes for the complexity of care associated with these patients. No prior study has investigated the impact of MMC treatment at pediatric hospitals. The authors sought to examine the effect of pediatric hospital designation on patients undergoing postnatal MMC repair to identify factors associated with maximizing improved patient outcomes.
The Nationwide Readmissions Database records from 2010 to 2018 were analyzed retrospectively to determine the effect of hospital designation on patient outcomes after postnatal MMC repair. Univariate and multivariate regression analyses of patient and hospital characteristics were conducted to evaluate if MMC repair at a designated pediatric hospital was independently associated with patient outcomes of perinatal infection rates, discharge disposition, and length of stay.
总数的6353 underw儿科患者ent postnatal MMC repair between 2010 and 2018, 2224 (35.0%) received care at a pediatric hospital. Those with an extreme level of disease burden as defined by the all patient refined diagnosis-related group severity of illness index were more likely to be treated at a pediatric hospital (p = 0.03). Patients undergoing repair at a pediatric hospital were also associated with a decreased likelihood of perinatal infection (OR 0.54, 95% CI 0.35–0.83, p = 0.005); greater likelihood of routine disposition (OR 4.85, 95% CI 2.34–10.06, p < 0.0001); and shorter length of stay (incidence rate ratio 0.88, 95% CI 0.77–0.995, p = 0.04).
Pediatric patients requiring intervention for postnatal repair of MMC may benefit from the multidisciplinary subspeciality care offered at pediatric hospitals. The authors found that postnatal repair of MMC at pediatric hospitals was associated with a greater likelihood of improved patient outcomes.
INCLUDE WHEN CITINGPublished online June 16, 2023; DOI: 10.3171/2023.5.PEDS22564.
DisclosuresDr. Mack reported the following: consultant for Rebound Therapeutics, Viseon Imperative Care, Integra, Q’Apel, Medtronic, Stream Biomedical, Spartan Micro, and Egret. He is also an investor in Cerebrotech, Q’Apel, Endostream, Viseon Imperative Care, Rebound Therapeutics, Stream Biomedical, Truvic, Spartan Micro, Radical Catheters, Vastrax, and Borvo.
CoppAJ,AdzickNS,ChittyLS,FletcherJM,HolmbeckGN,ShawGM.Spina bifida.Nat Rev Dis Primers.2015;1(1):15007.
BlountJP,BowmanR,DiasMS,HopsonB,PartingtonMD,RocqueBG.Neurosurgery guidelines for the care of people with spina bifida.J Pediatr Rehabil Med.2020;13(4):467–477.
McLoneDG,DiasMS.Complications of myelomeningocele closure.Pediatr Neurosurg.1991;17(5):267–273.
HannanEL,RaczM,KaveyRE,QuaegebeurJM,WilliamsR.Pediatric cardiac surgery: the effect of hospital and surgeon volume on in-hospital mortality.Pediatrics.1998;101(6):963–969.
WelkeKF,O’BrienSM,PetersonED,UngerleiderRM,JacobsML,JacobsJP.The complex relationship between pediatric cardiac surgical case volumes and mortality rates in a national clinical database.J Thorac Cardiovasc Surg.2009;137(5):1133–1140.
ContentoMN,VercilloRN,Malaga-DieguezL,et al.Center volume and kidney transplant outcomes in pediatric patients.Kidney Med.2020;2(3):297–30.6.
BucherBT,GuthRM,SaitoJM,NajafT,WarnerBW.Impact of hospital volume on in-hospital mortality of infants undergoing repair of congenital diaphragmatic hernia.Ann Surg.2010;252(4):635–642.
SmithER,ButlerWE,BarkerFGII.Craniotomy for resection of pediatric brain tumors in the United States, 1988 to 2000: effects of provider caseloads and progressive centralization and specialization of care.开云体育app官方网站下载入口.2004;54(3):553–565.
SmithER,ButlerWE,BarkerFGII.In-hospital mortality rates after ventriculoperitoneal shunt procedures in the United States, 1998 to 2000: relation to hospital and surgeon volume of care.J Neurosurg.2004;100(2 Suppl Pediatrics):90–97.
LewisCW,CarronJD,PerkinsJA,SieKCY,FeudtnerC.Tracheotomy in pediatric patients: a national perspective.Arch Otolaryngol Head Neck Surg.2003;129(5):523–529.
DonohoDA,WenT,LiuJ,et al.The effect of NACHRI children’s hospital designation on outcome in pediatric malignant brain tumors.J Neurosurg Pediatr.2017;20(2):149–157.
AlayonAL,HagertyV,HospedalesE,et al.Impact of insurance status, hospital ownership type, and children’s hospital designation on outcomes for pediatric neurosurgery patients following spasticity procedures in the USA.Childs Nerv Syst.2021;37(12):3881–3889.
McCormickPJ,LinHM,DeinerSG,LevinMA.Validation of the All Patient Refined Diagnosis Related Group (APR-DRG) risk of mortality and severity of illness modifiers as a measure of perioperative risk.J Med Syst.2018;42(5):81.
WangH,JohnsonC,RobinsonRD,et al.Roles of disease severity and post-discharge outpatient visits as predictors of hospital readmissions.BMC Health Serv Res.2016;16(1):564.
SimonTD,BerryJ,FeudtnerC,et al.Children with complex chronic conditions in inpatient hospital settings in the United States.Pediatrics.2010;126(4):647–655.
DynanL,GoudieA,SmithRB,FairbrotherG,SimpsonLA.Differences in quality of care among non-safety-net, safety-net, and children’s hospitals.Pediatrics.2013;131(2):30.4–311.
AdzickNS,ThomEA,SpongCY,et al.A randomized trial of prenatal versus postnatal repair of myelomeningocele.N Engl J Med.2011;364(11):993–1004.
ShlobinNA,YerkesEB,SwaroopVT,LamS,McLoneDG,BowmanRM.Multidisciplinary spina bifida clinic: the Chicago experience.Childs Nerv Syst.2022;38(9):1675–1681.
IskandarBJ,FinnellRH.Spina bifida.N Engl J Med.2022;387(5):444–450.
DemirN,PekerE,Gülşenİ,KocamanS,TuncerO,KırımiE.Powder topical rifampin for reducing infections after neural tube defect surgery in infants.World Neurosurg.2016;95:165–170.
FingerT,SchaumannA,PennacchiettiV,BührerC,ThomaleUW,SchulzM.Reduced rates of infection after myelomeningocele closure associated with standard perioperative antibiotic treatment with ampicillin and gentamicin.Childs Nerv Syst.2021;37(2):545–553.
AnegbeAO,ShokunbiMT,OyemoladeTA,BadejoOA.Intracranial infection in patients with myelomeningocele: profile and risk factors.Childs Nerv Syst.2019;35(11):2205–2210.
CherianJ,StaggersKA,PanIW,LoprestiM,JeaA,LamS.Thirty-day outcomes after postnatal myelomeningocele repair: a National Surgical Quality Improvement Program Pediatric database analysis.J Neurosurg Pediatr.2016;18(4):416–422.
AttenelloFJ,TuchmanA,ChristianEA,et al.Infection rate correlated with time to repair of open neural tube defects (myelomeningoceles): an institutional and national study.Childs Nerv Syst.2016;32(9):1675–1681.
RodriguesABD,KrebsVLJ,MatushitaH,de CarvalhoWB.Short-term prognostic factors in myelomeningocele patients.Childs Nerv Syst.2016;32(4):675–680.
BulbulA,CanE,BulbulLG,CömertS,NuhogluA.Clinical characteristics of neonatal meningomyelocele cases and effect of operation time on mortality and morbidity.Pediatr Neurosurg.2010;46(3):199–204.
BeuriatPA,PoirotI,HameuryF,et al.Postnatal management of myelomeningocele: outcome with a multidisciplinary team experience.World Neurosurg.2018;110:e24–e31.
ThibadeauJ,WalkerWOJr,CastilloJ,et al.Philosophy of care delivery for spina bifida.Disabil Health J.2020;13(2):100883.
BariME,HaiderG,MalikK,WaqasM,MahmoodSF,SiddiquiM.Outcomes of post-neurosurgical ventriculostomy-associated infections.Surg Neurol Int.2017;8(1):124.
de LissovoyG,FraemanK,HutchinsV,MurphyD,SongD,VaughnBB.Surgical site infection: incidence and impact on hospital utilization and treatment costs.Am J Infect Control.2009;37(5):387–397.
Abu HamdehS,LytsyB,Ronne-EngströmE.Surgical site infections in standard neurosurgery procedures—a study of incidence, impact and potential risk factors.Br J Neurosurg.2014;28(2):270–275.
CosperGH,HamannMS,StilesA,NakayamaDK.Hospital characteristics affect outcomes for common pediatric surgical conditions.Am Surg.2006;72(8):739–745.
RavalMV,CohenME,BarsnessKA,BentremDJ,PhillipsJD,ReynoldsM.Does hospital type affect pyloromyotomy outcomes? Analysis of the Kids’ Inpatient Database.Surgery.2010;148(2):411–419.
NguyenC,Hernandez-BoussardT,DaviesSM,BhattacharyaJ,KhoslaRK,CurtinCM.Cleft palate surgery: an evaluation of length of stay, complications, and costs by hospital type.Cleft Palate Craniofac J.2014;51(4):412–419.
JenHC,ShewSB.The impact of hospital type and experience on the operative utilization in pediatric intussusception: a nationwide study.J Pediatr Surg.2009;44(1):241–246.
McAteerJP,LaRiviereCA,DrugasGT,AbdullahF,OldhamKT,GoldinAB.Influence of surgeon experience, hospital volume, and specialty designation on outcomes in pediatric surgery: a systematic review.JAMA Pediatr.2013;167(5):468–475.
SamuelsS,KimballR,HagertyV,LeveneT,LeveneHB,SpaderH.Association of hospital characteristics with outcomes for pediatric neurosurgical accidental trauma patients.J Neurosurg Pediatr.2021;27(6):637–642.
StolarCJH.Best practice for infant surgery—a position statement from the American Pediatric Surgical Association.J Pediatr Surg.2008;43(9):1585–1586.
AlfordEN,HopsonBD,SafyanovF,et al.Care management and contemporary challenges in spina bifida: a practice preference survey of the American Society of Pediatric Neurosurgeons.J Neurosurg Pediatr.2019;24(5):539–548.
KemaloğluCA,Özyazganİ,ÜnverdiÖF.A decision-making guide for the closure of myelomeningocele skin defects with or without primary repair.J Neurosurg Pediatr.2016;18(2):187–191.
BevanR,Wilson-JonesN,BhattiI,PatelC,LeachP.How much do plastic surgeons add to the closure of myelomeningoceles?Childs Nerv Syst.2018;34(4):737–740.
MarreirosH,LoffC,CaladoE.Who needs surgery for pediatric myelomeningocele? A retrospective study and literature review.J Spinal Cord Med.2015;38(5):626–640.
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