This site usescookies, tags, and tracking settings to store information that help give you the very best browsing experience. Dismiss this warning

Myelomeningocele repair at pediatric hospitals: association with routine discharge and shorter hospital stay

Jane S. Han Departments ofNeurological Surgery and

搜索other papers by Jane S. Han in
jns
Google Scholar
PubMed
Close
MS
,
Shivani D. Rangwala Departments ofNeurological Surgery and

搜索other papers by Shivani D. Rangwala in
jns
Google Scholar
PubMed
Close
MD
,
Brandon B. Ge Departments ofNeurological Surgery and

搜索other papers by Brandon B. Ge in
jns
Google Scholar
PubMed
Close
BS
,
Kristie Q. Liu Departments ofNeurological Surgery and

搜索other papers by Kristie Q. Liu in
jns
Google Scholar
PubMed
Close
MS
,
Li Ding Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles; and

搜索other papers by Li Ding in
jns
Google Scholar
PubMed
Close
MD
,
William J. Mack Departments ofNeurological Surgery and

搜索other papers by William J. Mack in
jns
Google Scholar
PubMed
Close
MD
,
Susan Durham Department of Surgery, Division of Neurological Surgery, Children’s Hospital of Los Angeles, California

搜索other papers by Susan Durham in
jns
Google Scholar
PubMed
Close
MD, MS
,
Mark D. Krieger Department of Surgery, Division of Neurological Surgery, Children’s Hospital of Los Angeles, California

搜索other papers by Mark D. Krieger in
jns
Google Scholar
PubMed
Close
MD
, and
Frank J. Attenello Departments ofNeurological Surgery and

搜索other papers by Frank J. Attenello in
jns
Google Scholar
PubMed
Close
MD
Restricted access

Purchase Now

USD$45.00

JNS + Pediatrics - 1 year subscription bundle (Individuals Only)

USD$525.00

JNS + Pediatrics + Spine - 1 year subscription bundle (Individuals Only)

USD$624.00
USD$45.00
USD$525.00
USD$624.00
Print or Print + Online Sign in

OBJECTIVE

Postnatal repair for myelomeningocele (MMC) is a time-sensitive and technically challenging procedure. More experienced hospitals may provide improved outcomes for the complexity of care associated with these patients. No prior study has investigated the impact of MMC treatment at pediatric hospitals. The authors sought to examine the effect of pediatric hospital designation on patients undergoing postnatal MMC repair to identify factors associated with maximizing improved patient outcomes.

开云体育世界杯赔率

The Nationwide Readmissions Database records from 2010 to 2018 were analyzed retrospectively to determine the effect of hospital designation on patient outcomes after postnatal MMC repair. Univariate and multivariate regression analyses of patient and hospital characteristics were conducted to evaluate if MMC repair at a designated pediatric hospital was independently associated with patient outcomes of perinatal infection rates, discharge disposition, and length of stay.

RESULTS

总数的6353 underw儿科患者ent postnatal MMC repair between 2010 and 2018, 2224 (35.0%) received care at a pediatric hospital. Those with an extreme level of disease burden as defined by the all patient refined diagnosis-related group severity of illness index were more likely to be treated at a pediatric hospital (p = 0.03). Patients undergoing repair at a pediatric hospital were also associated with a decreased likelihood of perinatal infection (OR 0.54, 95% CI 0.35–0.83, p = 0.005); greater likelihood of routine disposition (OR 4.85, 95% CI 2.34–10.06, p < 0.0001); and shorter length of stay (incidence rate ratio 0.88, 95% CI 0.77–0.995, p = 0.04).

CONCLUSIONS

Pediatric patients requiring intervention for postnatal repair of MMC may benefit from the multidisciplinary subspeciality care offered at pediatric hospitals. The authors found that postnatal repair of MMC at pediatric hospitals was associated with a greater likelihood of improved patient outcomes.

ABBREVIATIONS

APR-DRG = all patient refined diagnosis-related group ; CCC = complex chronic conditions ; ICD-9 = International Classification of Diseases, Ninth Edition ; ICD-10 = International Classification of Diseases, Tenth Edition ; IRR = incidence rate ratio ; LOS = length of stay ; MCM = multidisciplinary care model ; MMC = myelomeningocele ; NRD = Nationwide Readmissions Database .

Supplementary Materials

    • Supplemental Tables 1 and 2 (PDF 453 KB)
  • Collapse
  • Expand
Illustration from Rizvi et al. (277–284). © Imran Rizvi, published with permission.
  • 1

    CoppAJ,AdzickNS,ChittyLS,FletcherJM,HolmbeckGN,ShawGM.Spina bifida.Nat Rev Dis Primers.2015;1(1):15007.

  • 2

    BlountJP,BowmanR,DiasMS,HopsonB,PartingtonMD,RocqueBG.Neurosurgery guidelines for the care of people with spina bifida.J Pediatr Rehabil Med.2020;13(4):467477.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 3

    McLoneDG,DiasMS.Complications of myelomeningocele closure.Pediatr Neurosurg.1991;17(5):267273.

  • 4

    HannanEL,RaczM,KaveyRE,QuaegebeurJM,WilliamsR.Pediatric cardiac surgery: the effect of hospital and surgeon volume on in-hospital mortality.Pediatrics.1998;101(6):963969.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 5

    WelkeKF,O’BrienSM,PetersonED,UngerleiderRM,JacobsML,JacobsJP.The complex relationship between pediatric cardiac surgical case volumes and mortality rates in a national clinical database.J Thorac Cardiovasc Surg.2009;137(5):11331140.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 6

    ContentoMN,VercilloRN,Malaga-DieguezL,et al.Center volume and kidney transplant outcomes in pediatric patients.Kidney Med.2020;2(3):29730.6.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 7

    BucherBT,GuthRM,SaitoJM,NajafT,WarnerBW.Impact of hospital volume on in-hospital mortality of infants undergoing repair of congenital diaphragmatic hernia.Ann Surg.2010;252(4):635642.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 8

    SmithER,ButlerWE,BarkerFGII.Craniotomy for resection of pediatric brain tumors in the United States, 1988 to 2000: effects of provider caseloads and progressive centralization and specialization of care.开云体育app官方网站下载入口.2004;54(3):553565.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 9

    SmithER,ButlerWE,BarkerFGII.In-hospital mortality rates after ventriculoperitoneal shunt procedures in the United States, 1998 to 2000: relation to hospital and surgeon volume of care.J Neurosurg.2004;100(2 Suppl Pediatrics):9097.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 10

    LewisCW,CarronJD,PerkinsJA,SieKCY,FeudtnerC.Tracheotomy in pediatric patients: a national perspective.Arch Otolaryngol Head Neck Surg.2003;129(5):523529.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 11

    DonohoDA,WenT,LiuJ,et al.The effect of NACHRI children’s hospital designation on outcome in pediatric malignant brain tumors.J Neurosurg Pediatr.2017;20(2):149157.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 12

    AlayonAL,HagertyV,HospedalesE,et al.Impact of insurance status, hospital ownership type, and children’s hospital designation on outcomes for pediatric neurosurgery patients following spasticity procedures in the USA.Childs Nerv Syst.2021;37(12):38813889.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 13

    McCormickPJ,LinHM,DeinerSG,LevinMA.Validation of the All Patient Refined Diagnosis Related Group (APR-DRG) risk of mortality and severity of illness modifiers as a measure of perioperative risk.J Med Syst.2018;42(5):81.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 14

    WangH,JohnsonC,RobinsonRD,et al.Roles of disease severity and post-discharge outpatient visits as predictors of hospital readmissions.BMC Health Serv Res.2016;16(1):564.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 15

    SimonTD,BerryJ,FeudtnerC,et al.Children with complex chronic conditions in inpatient hospital settings in the United States.Pediatrics.2010;126(4):647655.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 16

    DynanL,GoudieA,SmithRB,FairbrotherG,SimpsonLA.Differences in quality of care among non-safety-net, safety-net, and children’s hospitals.Pediatrics.2013;131(2):30.4311.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 17

    AdzickNS,ThomEA,SpongCY,et al.A randomized trial of prenatal versus postnatal repair of myelomeningocele.N Engl J Med.2011;364(11):9931004.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 18

    ShlobinNA,YerkesEB,SwaroopVT,LamS,McLoneDG,BowmanRM.Multidisciplinary spina bifida clinic: the Chicago experience.Childs Nerv Syst.2022;38(9):16751681.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 19

    IskandarBJ,FinnellRH.Spina bifida.N Engl J Med.2022;387(5):444450.

  • 20

    DemirN,PekerE,Gülşenİ,KocamanS,TuncerO,KırımiE.Powder topical rifampin for reducing infections after neural tube defect surgery in infants.World Neurosurg.2016;95:165170.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 21

    FingerT,SchaumannA,PennacchiettiV,BührerC,ThomaleUW,SchulzM.Reduced rates of infection after myelomeningocele closure associated with standard perioperative antibiotic treatment with ampicillin and gentamicin.Childs Nerv Syst.2021;37(2):545553.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 22

    AnegbeAO,ShokunbiMT,OyemoladeTA,BadejoOA.Intracranial infection in patients with myelomeningocele: profile and risk factors.Childs Nerv Syst.2019;35(11):22052210.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 23

    CherianJ,StaggersKA,PanIW,LoprestiM,JeaA,LamS.Thirty-day outcomes after postnatal myelomeningocele repair: a National Surgical Quality Improvement Program Pediatric database analysis.J Neurosurg Pediatr.2016;18(4):416422.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 24

    AttenelloFJ,TuchmanA,ChristianEA,et al.Infection rate correlated with time to repair of open neural tube defects (myelomeningoceles): an institutional and national study.Childs Nerv Syst.2016;32(9):16751681.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 25

    RodriguesABD,KrebsVLJ,MatushitaH,de CarvalhoWB.Short-term prognostic factors in myelomeningocele patients.Childs Nerv Syst.2016;32(4):675680.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 26

    BulbulA,CanE,BulbulLG,CömertS,NuhogluA.Clinical characteristics of neonatal meningomyelocele cases and effect of operation time on mortality and morbidity.Pediatr Neurosurg.2010;46(3):199204.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 27

    BeuriatPA,PoirotI,HameuryF,et al.Postnatal management of myelomeningocele: outcome with a multidisciplinary team experience.World Neurosurg.2018;110:e24e31.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 28

    ThibadeauJ,WalkerWOJr,CastilloJ,et al.Philosophy of care delivery for spina bifida.Disabil Health J.2020;13(2):100883.

  • 29

    BariME,HaiderG,MalikK,WaqasM,MahmoodSF,SiddiquiM.Outcomes of post-neurosurgical ventriculostomy-associated infections.Surg Neurol Int.2017;8(1):124.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 30.

    de LissovoyG,FraemanK,HutchinsV,MurphyD,SongD,VaughnBB.Surgical site infection: incidence and impact on hospital utilization and treatment costs.Am J Infect Control.2009;37(5):387397.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 31

    Abu HamdehS,LytsyB,Ronne-EngströmE.Surgical site infections in standard neurosurgery procedures—a study of incidence, impact and potential risk factors.Br J Neurosurg.2014;28(2):270275.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 32

    CosperGH,HamannMS,StilesA,NakayamaDK.Hospital characteristics affect outcomes for common pediatric surgical conditions.Am Surg.2006;72(8):739745.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 33

    RavalMV,CohenME,BarsnessKA,BentremDJ,PhillipsJD,ReynoldsM.Does hospital type affect pyloromyotomy outcomes? Analysis of the Kids’ Inpatient Database.Surgery.2010;148(2):411419.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 34

    NguyenC,Hernandez-BoussardT,DaviesSM,BhattacharyaJ,KhoslaRK,CurtinCM.Cleft palate surgery: an evaluation of length of stay, complications, and costs by hospital type.Cleft Palate Craniofac J.2014;51(4):412419.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 35

    JenHC,ShewSB.The impact of hospital type and experience on the operative utilization in pediatric intussusception: a nationwide study.J Pediatr Surg.2009;44(1):241246.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 36

    McAteerJP,LaRiviereCA,DrugasGT,AbdullahF,OldhamKT,GoldinAB.Influence of surgeon experience, hospital volume, and specialty designation on outcomes in pediatric surgery: a systematic review.JAMA Pediatr.2013;167(5):468475.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 37

    SamuelsS,KimballR,HagertyV,LeveneT,LeveneHB,SpaderH.Association of hospital characteristics with outcomes for pediatric neurosurgical accidental trauma patients.J Neurosurg Pediatr.2021;27(6):637642.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 38

    StolarCJH.Best practice for infant surgery—a position statement from the American Pediatric Surgical Association.J Pediatr Surg.2008;43(9):15851586.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 39

    AlfordEN,HopsonBD,SafyanovF,et al.Care management and contemporary challenges in spina bifida: a practice preference survey of the American Society of Pediatric Neurosurgeons.J Neurosurg Pediatr.2019;24(5):539548.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 40

    KemaloğluCA,Özyazganİ,ÜnverdiÖF.A decision-making guide for the closure of myelomeningocele skin defects with or without primary repair.J Neurosurg Pediatr.2016;18(2):187191.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 41

    BevanR,Wilson-JonesN,BhattiI,PatelC,LeachP.How much do plastic surgeons add to the closure of myelomeningoceles?Childs Nerv Syst.2018;34(4):737740.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 42

    MarreirosH,LoffC,CaladoE.Who needs surgery for pediatric myelomeningocele? A retrospective study and literature review.J Spinal Cord Med.2015;38(5):626640.

    • PubMed
    • Search Google Scholar
    • Export Citation

Metrics

All Time Past Year Past 30 Days
Abstract Views 486 486 91
Full Text Views 66 66 27
PDF Downloads 79 79 30.
EPUB Downloads 0 0 0
Baidu
map