Volume 32: Issue 3 (Sep 2023)
inJournal of Neurosurgery: Pediatrics-
Kaamya Varagur,John Murphy,Esther Ochoa,Gary B. Skolnick,Sybill D. Naidoo,Sean D. McEvoy,Jennifer M. Strahle, andKamlesh B. Patel
In Brief
Researchers utilized the area deprivation index (ADI) and the social vulnerability index to examine whether neighborhood disadvantage impacts interventions and outcomes of patients with craniosynostosis. Belonging to a more deprived ADI group was associated with greater risk of speech/language concerns and decreased likelihood of physician- or parent-reported desire for revision. Connecting families to community-based early intervention services and utilizing standardized clinic notes to document physical examination findings may help reduce existing disparities.
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Leonardo Domínguez,Claudio Rivas-Palacios,Mario M. Barbosa,Maria Andrea Escobar,Elvira Puello Florez, andEzequiel García-Ballestas
In Brief
objective of this study was to compare open surgery and endoscope-assisted surgery in a single center to treat children < 6 months of age with craniosynostosis. This study is unique because none of the patients (with the exception of those diagnosed with coronal synostosis) used helmet therapy for the correction of craniosynostosis. To the authors' knowledge, this is the first study conducted in non-North American and non-European children showing the outcomes in craniosynostosis management.
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Imran Rizvi,Rami R. Hallac,Emily L. Geisler,Jeyna K. Perez,Bar Y. Ainuz,Mark P. Pressler,Sarah A. Jackson,Gary B. Skolnick,Matthew D. Smyth,James R. Seaward,Christopher A. Derderian,Lisa R. David,Christopher M. Runyan,Kamlesh B. Patel, andAlex A. Kane
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Ildiko Hoffmann,Erin R. Lewis,Corrado Marini,John McNelis,Shankar Viswanathan,Jussi P. Posti,David A. Lieb, andMichael Lowery Wilson
In Brief
This pediatric venous thromboembolism (VTE) prediction tool was developed for patients with traumatic brain injury (TBI). Diagnosis of ventilator-associated pneumonia and presence of a central venous catheter were the strongest VTE risk factors. The calculated VTE risks in patients with isolated severe TBI were higher compared to the results from existing tools for a broad trauma population.
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Mani Ratnesh S. Sandhu,Wyatt B. David,Benjamin C. Reeves,Josiah J. Z. Sherman,Samuel Craft,Christina Jayaraj,Sam Boroumand,Mona Clappier,Alan Gutierrez,Margot Sarkozy,Andrew B. Koo,Dominick A. Tuason,Michael L. DiLuna, andAladine A. Elsamadicy
In Brief
objective of this study was to assess whether insurance status impacted healthcare resource utilization and outcomes in adolescent patients presenting with a spinal cord injury (SCI). The authors found that insurance status was not independently associated with obtaining imaging, undergoing surgery, hospital adverse events, or length of hospital stay. This study highlights the need to identify other patient- and hospital-related factors that may contribute to disparities in outcomes in adolescents presenting with SCI.
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Michael Egnor,Liu Yang,Racheed M. Mani,Susan M. Fiore, andPetar M. Djurić
In Brief
Researchers used mathematical analysis to compare the intracranial pressure dynamics of dogs to the dynamics of a simple electrical tank circuit. The dynamics were very similar. This study provides insight into the means by which the arterial pulse is buffered in the cranium, and suggests a new understanding of hydrocephalus and other disorders of intracranial dynamics.
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Vijay M. Ravindra,Hailey Jensen,Jay Riva-Cambrin,John C. Wellons III,David D. Limbrick Jr.,Jonathan Pindrik,Eric M. Jackson,Ian F. Pollack,Todd C. Hankinson,Jason S. Hauptman,Mandeep S. Tamber,Abhaya V. Kulkarni,Brandon G. Rocque,Curtis Rozzelle,William E. Whitehead,Jason Chu,Mark D. Krieger,Tamara D. Simon,Ron Reeder,Patrick J. McDonald,Nichol Nunn,John R. W. Kestle, andfor the Hydrocephalus Clinical Research Network
In Brief
The authors' objective was to investigate shunt management in children with abdominal pseudocysts–peritoneal reimplantation versus implantation in a nonperitoneal site. The primary outcome was shunt failure (infection/malfunction). No differences were found in overall shunt failure rate; however, noninfectious shunt revisions were more common in the nonperitoneal distal catheter sites and infection was a more common reason for failure after reimplantation in the abdomen. This study will inform the management of abdominal pseudocysts in children with hydrocephalus.
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Kristie Q. Liu,Shivani D. Rangwala,Talia A. Wenger,Mmerobasi U. Kanu,Jane S. Han,Li Ding,William J. Mack,Mark D. Krieger, andFrank J. Attenello
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Megan M. J. Bauman,Max B. Giesken,Ryan M. Naylor,Gesina F. Keating,Jonathan D. Schwartz, andDavid J. Daniels
In Brief
研究人员试图确定因素是predictive of tumor progression and/or the need for future tumor-directed treatment in pediatric patients with tectal plate gliomas. Patients with certain imaging characteristics or specific symptomatology at presentation were more likely to require future tumor-directed treatment. However, this patient population has excellent outcomes and survival overall, although there is still room for improvement in individualized treatment and disease course monitoring.
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Rakan Bokhari,Lior M. Elkaim,Nathan A. Shlobin,Naif M. Alotaibi,Abdulrahman J. Sabbagh,Alexander G. Weil,Saleh Baeesa,Roy W. R. Dudley,Jeffrey Atkinson, andJean-Pierre Farmer
In Brief
Vasospasm following brain tumor resection in children and youth is a rare complication with a poorly understood pathophysiology. The authors present their institutional experience with this rare entity and supplement it with a systematic review. The authors reported an incidence of 3.5% and showed that this complication's clinical course is not benign, with most children and youth having significant disability at long-term follow-up. This study represents the largest pediatric case series in the published literature, as well as the first systematic review of vasospasm after brain tumor resection that focuses on pediatric patients.
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Rebecca A. Reynolds,Diane J. Aum,Ignacio Gonzalez-Gomez,Michael Wong,Kaleigh Roberts,Sonika Dahiya,Luis F. Rodriguez,Jarod L. Roland, andMatthew D. Smyth
In Brief
This case series presents 5 patients with a pathological diagnosis of subependymal giant-cell astrocytoma (SEGA), but they did not otherwise meet the clinical criteria for a diagnosis of tuberous sclerosis. All subjects had negative germline tuberous sclerosis complex (TSC) test results. This study highlights the fact that although tumors may carry aTSC1orTSC2mutation, not all children with SEGA have tuberous sclerosis.
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Lisa F. Akiyama,Emma A. Roberts,Hillary A. Shurtleff,Dwight Barry,Russell P. Saneto,Edward J. Novotny,Christopher C. Young,Molly H. Warner,Jason S. Hauptman,Jeffrey G. Ojemann, andAhmad Marashly
In Brief
objective of the paper was to determine the clinical characteristics of patients in whom a small, subhemispheric resection failed, who went on to become seizure free after undergoing a hemispherectomy. The presence of a known hemispheric pathology such as Rasmussen encephalitis or a pathology involving > 2 lobes such as focal cortical dysplasia is predictive of subhemispheric surgery failure. This study helps in selecting patients who should proceed to a hemispheric surgery and avoid smaller, less successful, subhemispheric resections.
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Lauren L. Bystrom,Adam S. Levy,Erik C. Brown,Marytery Fajardo, andShelly Wang
In Brief
This paper is an individual patient data meta-analysis of 42 patients that evaluated the thalamic responsive neurostimulation (tRNS) outcomes for treating drug-resistant epilepsy (DRE). The authors found that tRNS resulted in a 73% seizure reduction rate in the entire population, with pediatric cases showing 75% seizure reduction and adult cases showing 69%. The authors additionally outlined other measures that should be included in future studies that use tRNS in order to better quantify this technique's success in treating DRE.
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Jane S. Han,Shivani D. Rangwala,Brandon B. Ge,Kristie Q. Liu,Li Ding,William J. Mack,Susan Durham,Mark D. Krieger, andFrank J. Attenello
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Audrey A. Grossen,Courtney R. Iser,Amy B. Leming,Virendra R. Desai, andDeepti G. Chrusciel
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